A static poisoning chamber is a commonly used equipment for conducting drug toxicity experiments. Animals are sealed in the chamber and given a certain dose of the drug, which is evenly dispersed in the chamber and exposed for an appropriate period of time. Observing the toxic reactions of animals within the specified time is applicable for the acute inhalation toxicity evaluation of drugs.

model: M301

M-301 typeThe main characteristics of a static poisoning box are:

·Suitable for gas and volatile (heatable volatile) test substances;

·Simple structure, easy operation, low drug consumption, suitable for acute toxicity experiments on small animals;

·Equipped with temperature, humidity, and gas concentration measuring devices;

·Equipped with a medication heating and volatilization tray, the test substance can be heated and volatilized;

·Fully transparent design, easy to observe the status and activity of animals inside the box;

·Equipped with a waste liquid outlet for easy cleaning;

·According to actual needs, suitable styles of poisoning boxes can be customized, such as square, cylindrical, and separate compartments for each mouse inside the box;

According to actual needs, a mobile poisoning chamber may also be used:

A dynamic poisoning chamber can atomize drugs, allergens, or other mixtures into extremely fine air soluble suspended particles and continuously feed them into a sealed box containing animals. Animals are exposed to it for the predetermined time in the experiment to complete the sensitization and stimulation process required for animal modeling; It can also be used as a whole body exposure system to expose animals to the whole body; There are currently two configurations for this system:

There are various sizes and specifications of exposed boxes to choose from, and customization can also be made according to needs:

(According to experimental requirements, different box sizes can be customized, and there are also various configuration matching schemes. Please call us for consultation.)

Exposure box model: S2

Note: Please choose the appropriate exposure box size based on the type and quantity of experimental animals exposed; According to the characteristics of the drug, nebulization and exposure devices are best used in biosafety cabinets.

Main features:

·Simultaneously modeling multiple animals with good consistency;

·Air supply function can be added according to demand to provide fresh air for the animals inside the box;

·Can be used with multiple atomizers: Different brands and models of atomizers have different particle sizes and atomization speeds, please choose according to your needs;

·Pharmacological experiments applicable to inhaled drugs in the lungs, taking OVA sensitization as an example, modeling with nebulization method requires less time than abdominal injection method;

·Yuyan Instrument Company can provide various mature matching solutions. Please call us for further communication;

Can be paired with Aeroneb Lab atomizer to atomize and push drugs into the atomizer box, continuously atomize and maintain a certain aerosol concentration in the exposure box:

The atomizer adopts palladium alloy vibrating grid technology, with a central orifice plate diameter of 5mm and 1000 precision formed micropores evenly distributed. It vibrates 128000 times per second, forming aerosol particle droplets that are very conducive to sedimentation into the lungs.

model: Aerogen Pro

Main advantages of the product:

·Both short-term and long-term experiments can ensure excellent and consistent output;
·Low atomization dose;
·The particle size distribution and particle object concentration have a high degree of repeatability;
·Medication can be filled at any time, and an automatic injection pump can also be used to add medication;
·Corrosion resistant shell design, durable and long-lasting;
·Highly integrated and compact in size;
·Easy to operate, no need for complex training work;

Main parameters of atomizing head：
·Small: Volume Median Diameter(VMD)
·Atomization rate:> 0.1mL/min
·Particle size: VMD (volume median diameter) ranging from 2.5 μ m to 4.0 μ m
·Drug residual amount:< 0.1mL

·Liquid atomized aerosols have many applications in scientific research, drug development, and quality testing;

Schematic diagram of atomizer connection:

Particle size distribution of atomized particles:

You can also choose Palas ® PLG Atomized Aerosol Generator:

The main technical parameters are as follows:

·Particulate solutes: such as engine oil, DEHS， paraffin oil
·Particle size: 50 nm -10 µ m
·Mass flow rate: 20 mg/h -
·Volume flow rate: approximately 2-110 l/min
·Power supply: 115/230V 50/60 Hz

According to your needs, you can also choose BGI Collison aerosol generator

MRE type Collison aerosol generator is a flat bottom spray designed by Microbiological Research Establishment. It has a variety of models including 1 nozzle, 3 nozzles and 6 nozzles. 3 nozzles are the most commonly used model.

The following image shows the animals exposed to the Collison aerosol generator with an animal poisoning chamber and compression pump

The specifications and dimensions of animal poisoning boxes can be customized according to customer needs:

We can also recommend more suitable atomization poisoning combination schemes based on laboratory needs. Please call us for consultation.

According to the experimental requirements, you may need a dust generator, aerosol generator, particle concentration meter, and aerosol concentration meter:

Dust particle generator, capable of atomizing dust and generating stable dust aerosols

Particle concentration measuring instrument, used for real-time measurement of particle concentration in exposed environments

Aerosol concentration measuring instrument, used for real-time measurement of aerosol concentration in exposed environments

For more detailed information, please call us for consultation.

：，

：

yuyanbio

： yuyanbio